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系所資訊
生技產業創新創業人才培育課程

系所行事曆
吳俊忠

專任特聘教授兼醫工學院院長 

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吳俊忠     

Wu, Jiunn-Jong

 

 

 
     
聯絡方式    
 jjwu1019@ym.edu.tw    
     
學歷    現職
美國加州聖地牙哥司貴寶研究機構 分子生物醫學部博士後研究員
美國賓州費城天普大學 微生物暨免疫研究所博士
美國賓州費城湯瑪士傑佛遜大學 臨床微生物研究所碩士
美國賓州費城湯瑪士傑佛遜大學醫事技術學系學士
 
 
  陽明大學生物醫學暨工程學院 院長
  陽明大學醫學生物技術暨檢驗學系 教授
  成功大學醫學院 醫學檢驗生物技術學系 特聘教授
  台灣微生物學會 理事長
  社團法人中華民國醫事檢驗師公會全國聯合會 理事長
 
 
 
 
 
經歷
  • 成功大學 傳染性疾病及訊息研究中心 主任
  • 成功大學醫學院 行政副院長
  • 成功大學醫學院 分子醫學研究所教授兼所長
  • 成功大學醫學院 教師發展中心主任
  • 衛生福利部 疾病管制署 咨詢委員
  • 教育部 生物技術科技教育改進計劃 分子檢驗教學資源中心 召集人
  • 成功大學生物科技中心 企劃組組長
  • 成功大學醫學院醫事技術學系教授兼主任
  • 國家衛生研究院臨床研究組南臺灣感染症訓練計劃教育委員
  • 成功大學醫學院附設醫院病理部醫事檢驗師
  • 成功大學醫學院醫事技術學系副教授
  • 馬偕醫院檢驗科醫檢師
 
榮譽
  • 美國微生物學院院士 (2013)
  • 成功大學特聘教授 (92, 95, 98, 101學年度)
  • 成功大學醫學院 教學特優教師 (82學年度) 
  • 成功大學教學優良教師 (97學年度)
  • 成功大學醫學院 服務特優教師 (94學年度)
  • 成功大學優良導師 (99學年度)
  • 台灣醫事檢驗學會年度最佳論文獎 (1997, 2003)
  • 台灣醫事檢驗學會年度學術論文獎 基礎研究組 (2006, 2009)
  • 台灣微生物學會 養樂多文教基金會特優論文獎 (2007, 2008, 2011)
 
研究方向
臨床微生物、細菌抗藥性、細菌致病機轉、感染管制
 
研究著作
  1. Chang WH, Wang CH, Lin CL, Wu JJ, Lee MS, Lee GB. 2015 April. Rapid detection and typing of live bacteria from human joint fluid samples by utilizing an integrated microfluidic system. Biosensors and Bioelectronics 66:148-154 (SCI)
  2. Kao CY, Chen JW, Huang YT, Sheu SM, Sheu BS, and Wu JJ*. 2015 Feb. Genome sequence and annotation of Helicobacter pylori strain HP238, isolated from a Taiwanese patient with mucosa-associated lymphoid tissue lymphoma. Genome Announcements 3(1). pii: e00006-15. doi: 10.1128/genomeA.00006-15. (SCI)
  3. Yan JJ, Wang MC, Zheng PX, Tsai LH, Wu JJ. 2015 Feb. Associations of the major international high-risk resistant clones and virulent clones with specific ompK36 allele groups in Klebsiella pneumoniae in Taiwan. New Microbes and New Infections 5:1-4 (SCI)
  4. Kao CY and Wu JJ*. 2015 Mar. Carbapenem resistance: epidemiology, mechanisms and screening methods. Journal of Biomedical and Laboratory Sciences 27(1):1-9 (mini review).
  5. Jean SS, Lee WS, Bai KJ, Yu KW, Hsu CW, Yu KW, Liao CH, Chang FY, Ko WC, Wu JJ, Chen YH, Chen YS, Liu JW, Lu MC, Liu CY, Chen RJ, Hsueh PR. 2015 Apr. Carbapenem susceptibility among Escherichia coli, Klebsiella pneumoniae, and Enterobacter cloacae isolates obtained from patients in intensive care units in Taiwan in 2005, 2007, and 2009. Diagnostic Microbiology and Infectious Disease 81(4):290-295 (SCI)
  6. Lin WH, Tseng CC, Wu AB, Yang DC, Cheng SW, Wang MC*, and Wu JJ*. 2015 June. Clinical and microbiological characteristics of Klebsiella pneumoniae isolated from peritoneal dialysis-related peritonitis in southern Taiwan.  Journal of Microbiology Immunology and Infection 48 (3): 276-283 (SCI, equal contribution)
  7. Wang MC, Lin WH, Yan JJ, Fang HY, Kuo TH, Tseng CC, and Wu JJ*. 2015 Aug. Earlier identification of blood stream infection pathogens using blood culture system and matrix-assisted laser desorption-ionization time of flight mass spectrometry. Journal of Microbiology Immunology and Infection 48(4):419-424. (SCI)
  8. Kao CY and Wu JJ*. 2015. Sep. The challenge of fluoroquinolone resistance: epidemiology, mechanisms, and clinical impact. Journal of Biomedical Laboratory Science 27(3):77-86 (review article)
  9. Yan JJ, Zheng PX, Wang MC, Tsai SH, Wang LR, and Wu JJ. 2015 Oct. Allocation of Klebsiella pneumoniae bloodstream isolates into four distinct groups by ompK36 typing in a Taiwanese university hospital. Journal of Clinical Microbiology 53:3256-3263 (SCI)
  10. Kao CY, Chen CA, Liu YF, Wu HM, Chiou CS, Yan JJ, and Wu JJ*. 2015 Molecular characterization of antimicrobial susceptibility of Salmonella isolates: First identification of a plasmid carrying qnrD or oqxAB in Taiwan. Journal of Microbiology Immunology and Infection 14-MAY-2015 pii: S1684-1182(15)00753-7. doi: 10.1016/j.jmii.2015.03.004. [Epub ahead of print] (SCI)
  11. Lu SL, Kao CF, Chen HW, Yang YS, Liu CC, Anderson R, Wu JJ*, and Lin YS*. 2015 Sep-Oct. Insufficient acidification of autophagosomes facilitates group A streptococcus survival and growth in endothelial cells. mBio 6(5):e01435-15. doi:10.1128/mBio.01435-15. (SCI, equal contribution)
  12. Chang WL, Yang HB, Cheng HC, Yeh YC, Kao CY, Wu JJ, Lu CC, and Sheu BS. 2015 Dec. Intracellular osteopontin induced by CagA-positive Helicobacter pylori promotes beta-catenin accumulation and interleukin-8 secretion in gastric epithelial cells. Helicobacter. 20(6): 476-484. (SCI)
  13. Zheng PX, Chan YC, Chiou CS, Chiang-Ni C, Wang SY, Tsai PJ, Chuang WJ, Lin YS, Liu CC, and Wu JJ*. 2015 Dec. Clustered regularly interspaced short palindromic repeats are emm type-specific in highly prevalent group A streptococci. PLoS One 10(12):e0145223 (SCI)
  14. Chiang-Ni C, Zheng PX, Wang S, Tsai PJ, Chuang WJ, Lin YS, Liu CC and Wu JJ*. 2016 Jan. Epidemiology analysis of Streptococcus pyogenes in a hospital in southern Taiwan by use of the updated emm cluster typing system. Journal of Clinical Microbiology 54(1):157-162 (SCI)
  15. Kao CY, Sheu BS, and Wu JJ*. 2016 Feb. Helicobacter pylori infection: an overview of bacterial virulence factors and pathogenesis. Biomedical Journal 39(1):14-23 (review article, SCI). 
  16. Kao CY, Udval U, Wu HM, Bolormaa E, Yan, JJ, Khosbayar T*, and Wu JJ*. 2016 Mar. First characterization of fluoroquinolone resistance mechanisms in CTX-M- producing Escherichia coli from Mongolia. Infection, Genetics and Evolution 38:79-81 (SCI, equal contribution) 
  17. Chao CY, Wang CH, Che YJ, Kao CY, Wu JJ, and Lee GB. 2016 Apr. An integrated microfluidic system for diagnosis of the resistance of Helicobacter pylori to quinolone-based antibiotics. Biosensor & Bioelectronics 78:281-289 (SCI) 
  18. Zheng PX, Fang HY, Yang HB, Tien NY, Wang MC, and Wu JJ* 2016 Apr.  Lactobacillus pentosus strain LPS16 produces lactic acid, inhibiting multidrug resistant Helicobacter pylori. Journal of Microbiology Immunology and Infection 49(2):168-174 (SCI)
  19. Chen CL, Wu YY, Lin CF, Kuo CF, Han CL, Wang SY, Chuang WJ, Chen CY, Wu JJ, Tsai PJ, Liu CC, and Lin YS. 2016 May. Streptococcal pyrogenic exotoxin B inhibits apoptotic cell clearance by macrophages through protein S cleavage. Scientific Reports 6:26026. (SCI)
  20. Hung JH, Chang TC, Wu JJ, Lai CC, Huang FC, and Huang YH. 2016 Apr. A cluster of Mycobacterium massiliense keratitis in foundry workers. Clinical Microbiology and Infection 22(4):385. e5-8 (SCI)
  21. Lin WH, Hwang JC, Tseng CC, Chang YT, Wu AB, Yan JJ, Wu JJ* and Wang MC*. 2016 May. Matrix-assisted laser desorption ionization-time of flight mass spectrometry accelerates pathogen identification and may confer benefit in the outcome of peritoneal dialysis-related peritonitis. Journal of Clinical Microbiology 54(5):1381-1383. (SCI, equal contribution) 
  22. Kao CY, Chen SS, Hung KH, Wu HM, Hsueh PR, Yan JJ, and Wu JJ*. 2016 June. Overproduction of active efflux pump and variations of OprD dominant in imipenem-resistant Pseudomonas aeruginosa isolated from patients with bloodstream infections in Taiwan. BMC Microbiology 16(1):107 (SCI) 
  23. Kao CY, Wu HM, Lin WH, Tseng CC, Yan JJ, Wang MC, Teng CH, and Wu JJ*. 2016 Aug. Plasmid-mediated quinolone resistance determinants in quinolone-resistant Escherichia coli isolated from patients with bacteremia in a university hospital in Taiwan, 2001-2015. Scientific Reports 6:32281 (SCI) 
  24. Kao CY, Udval U, Huang YT, Wu HM, Huang AY, Bolormaa E, Yan, JJ, Urangoo Z, Batbaatar G, Khosbayar T*, and Wu JJ*. 2016 Oct. Molecular characterization of extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella spp. isolates in Mongolia. Journal of Microbiology Immunology and Infection 49: 692-700. (SCI, equal contribution)
  25. Su YL, Huang HL, Huang BS, Chen PC, Chen CS, Wang HL, Lin PH, Chieh MS, Wu JJ, Yang JC and Chow LP. 2016 Nov. Combination of OipA, BabA, and SabA as candidate biomarkers for predicting Helicobacter pylori-related gastric cancer. Scientific Reports 6:36442 (SCI)
  26. Chiang-Ni C, Chu TP, Wu JJ, and Chiu CH. 2016 Nov. Repression of Rgg but not upregulation LacD.1 in emm1-type covS mutant mediates the SpeB repression in group A streptococcus. Frontiers in Microbiology 7:1935 (SCI)
  27. Jean SS, Lee WS, Yu KW, Liao CH, Hsu CW, Chang FY, Ko WC, Chen RJ, Wu JJ, Chen YH, Chen YS, Liu JW, Lu MC, Lam C, Liu CY, and Hsueh PR. 2016 Dec. Rates of susceptibility of carbapenems, ceftobiprole, and colistin against clinically important bacteria collected from intensive care units in 2007: Results from the Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART). Journal of Microbiology Immunology and Infection 49(6):969-976. doi: 10.1016/j.jmii.2014.12.008. (SCI)
  28. Chiang-Ni C, Nian SY, Wu JJ, and Chen CJ. 2016 Dec. Oxygen-dependent phenotypic variation in group A streptococcus. Journal of Microbiology Immunology and Infection 49(6):837-842 doi: 10.1016/j.jmii.2014.11.010. (SCI)
  29. Lin WH, Zheng PX, Tseng CC, Liu TL, Wang MC*, and Wu JJ*. 2016 Dec. Complete genome sequence of community-acquired Klebsiella pneumoniae KP36, a strain isolated from a patient with an upper urinary tract infection. 2016 Genome Announcements 4(6). pii: e01403-16. doi: 10.1128/genomeA.01403-16. (SCI, equal contribution) 
  30. Kao CY, Yan JJ, Lin YC, Zheng PX, and Wu JJ*. 2017 Mar. Complete genome sequence of carbapenem-resistant Klebsiella pneumoniae strain 1756, isolated from a pus specimen. Genome Announcements 5(13) e00066-17 (SCI)
  31. Chang WH, Yu JC, Yang SY, Lin YC, Wang CH, You HL, Wu JJ, Lee MS, and Lee GB. 2017 Mar. Vancomycin-resistant gene identification from live bacteria on an integrated microfluidic system by using low temperature lysis and loop-mediated isothermal amplification. Biomicrofluidics 11(2):024101 (SCI)
  32. Kao CY, Chen JW, Wang S, Sheu BS, and Wu JJ*. 2017 Mar. Helicobacter pylori J99 jhp0106 gene, under the control of CsrA/RpoN regulatory system, modulates flagella formation and motility. Frontiers in Microbiology 8: doi: 10.3389/fmicb.2017.00483 (SCI)
  33. Kao CH, Tsao N, Hsieh IC, Lin YS, Wu JJ, Yu-Ting and Hung YT. 2017 Mar. Immunization with a streptococcal multiple-epitope recombinant protein protects mice against invasive group A streptococcal infection. PLoS One 29;12(3):e0174464. doi: 10.1371/journal.pone.0174464. (SCI)
  34. Chen SL, Chang WH, Wang CH, You HL, Wu JJ, Lee MS and Lee GB. 2017. An integrated microfluidic system for live bacteria detection from human joint fluid samples by using ethidium monoazide and loop-mediated isothermal amplification. Microfluidics and Nanofluidics, DOI: 10.1007/s10404-017-1913-8, 2017 (SCI)
  35. Chen HM, Zheng PX, Wang LR, Wu JJ and Yan JJ. 2017. Multilocus sequence typing of carbapenemase-producing Enterobacter cloacae bloodstream isolates between 2002 and 2013 in a Taiwanese university hospital. Journal of Global Antimicrobial Resistance 2017 May 30. pii: S2213-7165(17)30068-1. doi: 10.1016/j.jgar.2017.05.006. [Epub ahead of print]
  36. Tseng CC, Wang MC, Lin WH, Liao IC, Chen WC, Teng CH, Yan JJ, Wu AB, and Wu JJ*. 2017. Role of class II P-fimbriae and cytokine response in the pathogenesis of Escherichia coli kidney infection in diabetic mice. Journal of Microbiology, Immunology and Infection 2017 Jun 29. pii: S1684-1182(17)30099-3. doi: 10.1016/j.jmii.2017.06.003. [Epub ahead of print] (SCI)
  37. Cheng YL, Wu YW, Kuo CF, Lu SL, Liu FT, Anderson R, Lin CF, Liu YL, Wang WY, Chen YD, Zheng PX, Wu JJ*, and Lin YS*. 2017 July. Galectin-3 inhibits Galectin-8/Parkin-mediated ubiquitination of group A streptococcus. MBiol 8(4): pii: e00899-17. doi: 10.1128/mBio.00899-17 (SCI, equal contribution)
  38. Lee AY, Kao CY, Wang YK, Lin SY, Lai TY, Sheu BS, Lo CJ*, and Wu JJ*. 2017 Aug. Inactivation of ferric uptake regulator (Fur) attenuates Helicobacter pylori J99 motility by disturbing the flagellar motor switch and autoinducer-2 production. Helicobacter 22(4) doi: 10.1111/hel.12388. (SCI, equal contribution)
  39. Zheng PX, Chan YC, Chiou CS, Hsieh CL, Chiang-Ni C, and Wu JJ*. 2017 Dec. Highly prevalent emmSTG840.0 and emmSTC839.0 types of erythromycin non-susceptible group G streptococcus isolated from bacteremia in southern Taiwan. Journal of Microbiology, Immunology and Infection 50:831-838 (SCI)