專任副教授 

黃智生     

Jason C. Huang

☏ 02-2826-7148

✉ jchuang2@ym.edu.tw

〒 Institute of Biotechnology in Medicine, National Yang Ming University, No. 155, Sec. 2, Linong St., Beitou District, Taipei City 112, Taiwan (R.O.C.)

1.  禽流感感冒病毒與樹突狀細胞之間的交互作用
2. 大腸直腸癌調控癌症轉移與幹細胞的基因研究
3. 自體免疫小鼠疾病模型的建立
4. 諾羅病毒疫苗載體的開發

1. Luong, H.M., Wang, S.F., Trao, V.T., Chen, M., Huang, J.C., Cam, P.D. Lin, Y.T. and Chen, Y.M. Retrospective survey of avian influenza H5N1 infection in Northern Vietnam by using a combinational serologic assay. Health. 2012, 4:974-982
2. Hwang, K.P., Wu, F.T., Bányai, K., Wu, H.S., Yang, D.C., Huang, Y.C., Lin, J.S., Hsiung, C.A., Huang, J.C., Jiang, B., and Gentsch, J.R. Identification of porcine rotavirus-like genotype P[6] strains in Taiwanese children. J Med Microbiol. 2012 61(7)990-997.
3. Wu, F.T., Bányai, K., Huang, J.C., Wu, H.S., Chang, F.Y., Hsiung, C.A., Huang, Y.C., Lin, J.S., Hwang, K.P., Jiang, B., and Gentsch, J.R. Human infection with novel G3P[25] rotavirus strain in Taiwan. Clin Microbiol Infect. 2011;17(10):1570-1573
4. Wu, F.T., Banyai, K., Huang, J.C., Wu, H.S., Chang, F.Y., Yang, J.Y., Hsiung, C.A., Huang, Y.C., Lin, J.S., Hwang, K.P., Jiang, B.,and Gentsch, J.R. Diverse origin of P[19] Rotaviruses in children with acute diarrhea in Taiwan: Detection of novel lineages of the G3, G5, G9 VP7 genes. J Med Virol 2011, 83 (7):1279-1287
5. Lee, C.W., Leu, S.J., Tseng, R.Y., Wang, S.F., Tsai, S.C., Sun, K.H., Chen, R.H. and Huang, J.C.* Latent membrane protein 1 of Epstein-Barr virus regulates death associated protein kinase 1 in lymphoblastoid cell line. Virology 2011, 413(1):19-25
6. Chang, Y.F*., Wang, S.F.*, Huang, J.C.*, Su, L.C., Yao, L., Li, Y.C., Wu, S.C., Chen, Y.M., Hsieh, J.P. and Chou, C. Detection of swine-origin influenza A (H1N1) viruses using a localized surface Plasmon coupled fluorescence fiber-optic biosensor. Biosens Bioelectron. 2010 26(3):1068-1073
7. Wang, S.F., Yao , L., Liu, S.J., Chong, P., Chen,Y.M., Huang, J.C.* Identifying conserved DR1501-restricted CD4+ T cell epitopes in avian H5N1 hemagglutinin proteins. Viral Immunol. 2010 23(6):585-593
8. Huang, J.C., Chang, Y.F., Chen, K.H., Su, L.C., Lee, C.W., Chen, C.C., Chen, Y.M., and Chou, C. Detection of severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein in human serum using a localized surface plasmon coupled fluorescence fiber-optic biosensor. Biosens Bioelectron. 2009, 25(2):320-325
9. Wang, S.F., Lee, Y.M., Chan, Y.J., Liu, H.F., Yen, Y.F., Liu, W.T., Huang, J.C*., and Chen, Y.M. Influenza A Virus in , 1980-2006:Phylogenetic and antigenic characteristics of the hemagglutinin gene. J Med Virol 2009, 81 (8):1457-1470
10. Peng, S.Y., Chu, T.H., Wang, I.C., Chung, W.C., Yu, K.W., Tsaihong, J.C., Huang, J.C., and Fan, P.C. Infection of normal C3H/HeN mice with Taenia saginata asiatica oncospheres. Res Vet Sci 2009;86(2):261-266
11. Wang, S.F., Chen, K.H., Thitithanyanont, A., Yao , L., Lee, Y.M., Chan, Y.J., Liu, S.J., Chong, P., Liu, W.T., Huang, J.C.*., and Chen, Y.M. Generating and characterizing monoclonal and polyclonal antibodies against avian H5N1 hemagglutinin protein. Biochem Biophy Res Commun 2009;382(4)691-696
12. Song, Y.C., Sun, G.H., Lee, T.P., Huang, J.C., Yu, C.L., Chen, C.H., Tang, S.J., Sun, K.H. Arginines in the CDR of anti-dsDNA autoantibodies facilitate cell internalization via electrostatic interactions. Eur J Immunol. 2008; 38 (11):3178-3190
13. Lee, T.P., Leu, S.J., Huang, J.C., Song,Y.C., Jhou, R.S., Tang,S.J., and Sun, K.H. Anti-ribosomal P autoantibody triggers IL-10 over-production via PI3K-dependent signaling pathways in LPS-activated macrophages. Immunology. 2008;127(7):91-102
14. Wang, S.F.*, Huang, J.C.*, Lee, Y.M., Liu, S.J., Chan, Y.J., Chau, Y.P., Chong, P., and Chen, Y.M. DC-SIGN mediates avian H5N1 influenza virus infection in cis and in trans. Biochem Biophys Res Commun. 2008.373(4):561-566
15. Sahu, G.K., McNearney, T., Evans, A., Turner, A., Weaver, S., Huang, J.C., Baron, S., Paar, D. and Cloyd, M.W. Transient or occult HIV infection may occur more frequently than progressive infections: Changing the paradigm about HIV persistence. Arch Virol 2005;19:131-145.
16. Huang, J.C., Ober, R.J., and Ward, E.S. The central residues of a T cell receptor sequence motif are key determinants of autoantigen recognition in murine experimental autoimmune encephalomyelitis.  Eur J Immunol 2005. 35(1):299-304.
17. Huang, J.C., Vestberg, M., Minguela, A., Holmdahl, R., Ward, E.S. Analysis of autoreactive T cells associated with murine collagen-induced arthritis using peptide-MHC multimers, Int. Immunol. 2004. 16(2):283-93.
18. Huang, J.C., Han, M., Minguela, A., Pastor, S., Qadri, A., Ward, E.S. T cell recognition of distinct peptide:I-Au conformers in murine experimental autoimmune encephalomyelitis. J. Immunol. 2003. 171(5):2467-77.
19. Chen, J.J., Huang J.C., Shirtliff, M., Briscoe, E., Ali, S., Cesani, F., Paar, D., Cloyd, M.W. CD4 lymphocytes in the blood of HIV(+) individuals migrate rapidly to lymph nodes and bone marrow: support for homing theory of CD4 cell depletion. J. Leukoc. Biol. 2002. 72(2):271-8.
20. Sahu, G.K., Chen, J.J., Huang, J.C., Ramsey, K.M., Cloyd, M.W. Transient or occult HIV-1 infection in high-risk adults. AIDS. 2001.15(9):1175-7.